Role of Clusterin in Cancer and Disease leaf node


URI

https://openalex.org/T14364

Label

Role of Clusterin in Cancer and Disease

Description

This cluster of papers explores the multifaceted role of Clusterin, a chaperone protein, in cancer development, progression, and therapy. It investigates its involvement in apoptosis inhibition, TGF-ß signaling modulation, angiogenesis promotion, chemoresistance, and its potential as a biomarker for various cancers. The papers also discuss the implications of Clusterin in metastasis, particularly in prostate cancer.

Implementation

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@prefix owl: <http://www.w3.org/2002/07/owl#> .
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@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://openalex.org/T14364> a skos:Concept ;
    rdfs:label "Role of Clusterin in Cancer and Disease"@en ;
    rdfs:isDefinedBy openalex: ;
    owl:sameAs <https://en.wikipedia.org/wiki/Clusterin>,
        <https://openalex.org/T14364> ;
    skos:broader oasubfields:2730 ;
    skos:definition "This cluster of papers explores the multifaceted role of Clusterin, a chaperone protein, in cancer development, progression, and therapy. It investigates its involvement in apoptosis inhibition, TGF-ß signaling modulation, angiogenesis promotion, chemoresistance, and its potential as a biomarker for various cancers. The papers also discuss the implications of Clusterin in metastasis, particularly in prostate cancer."@en ;
    skos:inScheme openalex: ;
    skos:prefLabel "Role of Clusterin in Cancer and Disease"@en ;
    openalex:cited_by_count 106730 ;
    openalex:works_count 5910 .