Cholesterol Metabolism and Atherosclerosis leaf node


URI

https://openalex.org/T11618

Label

Cholesterol Metabolism and Atherosclerosis

Description

This cluster of papers focuses on the intricate mechanisms of cholesterol metabolism, including the roles of key regulators such as LXR and SREBP, the impact on atherosclerosis, and the involvement of specific proteins like ABCA1 in processes such as cholesterol efflux from cells. It also delves into the effects of phytosterols on lipid levels and the interplay between cholesterol homeostasis and inflammation in conditions like atherosclerosis.

Implementation

@prefix oasubfields: <https://openalex.org/subfields/> .
@prefix openalex: <https://lambdamusic.github.io/openalex-hacks/ontology/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://openalex.org/T11618> a skos:Concept ;
    rdfs:label "Cholesterol Metabolism and Atherosclerosis"@en ;
    rdfs:isDefinedBy openalex: ;
    owl:sameAs <https://en.wikipedia.org/wiki/Cholesterol_metabolism>,
        <https://openalex.org/T11618> ;
    skos:broader oasubfields:2746 ;
    skos:definition "This cluster of papers focuses on the intricate mechanisms of cholesterol metabolism, including the roles of key regulators such as LXR and SREBP, the impact on atherosclerosis, and the involvement of specific proteins like ABCA1 in processes such as cholesterol efflux from cells. It also delves into the effects of phytosterols on lipid levels and the interplay between cholesterol homeostasis and inflammation in conditions like atherosclerosis."@en ;
    skos:inScheme openalex: ;
    skos:prefLabel "Cholesterol Metabolism and Atherosclerosis"@en ;
    openalex:cited_by_count 1135278 ;
    openalex:works_count 35385 .