https://openalex.org/T10678
This cluster of papers focuses on the use of cyclooxygenase-2 (COX-2) inhibitors, such as rofecoxib, celecoxib, and naproxen, in the context of inflammation and cancer. It explores the gastrointestinal and cardiovascular toxicity, chemopreventive effects, and potential risks associated with these drugs. The cluster also delves into the molecular biology of prostaglandins, particularly prostaglandin E2, and their role in modulating immune responses and promoting cancer growth.
@prefix oasubfields: <https://openalex.org/subfields/> .
@prefix openalex: <https://lambdamusic.github.io/openalex-hacks/ontology/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
<https://openalex.org/T10678> a skos:Concept ;
rdfs:label "Cyclooxygenase-2 Inhibitors in Inflammation and Cancer"@en ;
rdfs:isDefinedBy openalex: ;
owl:sameAs <https://en.wikipedia.org/wiki/Cyclooxygenase-2_inhibitor>,
<https://openalex.org/T10678> ;
skos:broader oasubfields:2736 ;
skos:definition "This cluster of papers focuses on the use of cyclooxygenase-2 (COX-2) inhibitors, such as rofecoxib, celecoxib, and naproxen, in the context of inflammation and cancer. It explores the gastrointestinal and cardiovascular toxicity, chemopreventive effects, and potential risks associated with these drugs. The cluster also delves into the molecular biology of prostaglandins, particularly prostaglandin E2, and their role in modulating immune responses and promoting cancer growth."@en ;
skos:inScheme openalex: ;
skos:prefLabel "Cyclooxygenase-2 Inhibitors in Inflammation and Cancer"@en ;
openalex:cited_by_count 2085181 ;
openalex:works_count 88291 .