Chemistry of Pyrrolobenzodiazepines leaf node


URI

https://openalex.org/T13105

Label

Chemistry of Pyrrolobenzodiazepines

Description

This cluster of papers focuses on the chemistry, synthesis, and biological evaluation of pyrrolobenzodiazepines, a class of DNA-interactive agents with potent antitumour activity. The research covers topics such as asymmetric synthesis, cross-linking agents, cytotoxicity, and their application in natural product synthesis.

Implementation

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<https://openalex.org/T13105> a skos:Concept ;
    rdfs:label "Chemistry of Pyrrolobenzodiazepines"@en ;
    rdfs:isDefinedBy openalex: ;
    owl:sameAs <https://en.wikipedia.org/wiki/Pyrrolobenzodiazepine>,
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    skos:broader oasubfields:1605 ;
    skos:definition "This cluster of papers focuses on the chemistry, synthesis, and biological evaluation of pyrrolobenzodiazepines, a class of DNA-interactive agents with potent antitumour activity. The research covers topics such as asymmetric synthesis, cross-linking agents, cytotoxicity, and their application in natural product synthesis."@en ;
    skos:inScheme openalex: ;
    skos:prefLabel "Chemistry of Pyrrolobenzodiazepines"@en ;
    openalex:cited_by_count 93611 ;
    openalex:works_count 11398 .