https://openalex.org/T13971
This cluster of papers focuses on the chemistry, biology, and synthesis of antitumor antibiotics, particularly tetrahydroisoquinoline compounds such as Ecteinascidin. It covers topics such as total synthesis, marine-derived compounds, asymmetric synthesis, and DNA binding mechanisms. The research also explores the pharmacological activities and potential clinical utility of these compounds.
@prefix oasubfields: <https://openalex.org/subfields/> .
@prefix openalex: <https://lambdamusic.github.io/openalex-hacks/ontology/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
<https://openalex.org/T13971> a skos:Concept ;
rdfs:label "Chemistry and Biology of Antitumor Antibiotics"@en ;
rdfs:isDefinedBy openalex: ;
owl:sameAs <https://en.wikipedia.org/wiki/Tetrahydroisoquinoline_antitumor_antibiotics>,
<https://openalex.org/T13971> ;
skos:broader oasubfields:1306 ;
skos:definition "This cluster of papers focuses on the chemistry, biology, and synthesis of antitumor antibiotics, particularly tetrahydroisoquinoline compounds such as Ecteinascidin. It covers topics such as total synthesis, marine-derived compounds, asymmetric synthesis, and DNA binding mechanisms. The research also explores the pharmacological activities and potential clinical utility of these compounds."@en ;
skos:inScheme openalex: ;
skos:prefLabel "Chemistry and Biology of Antitumor Antibiotics"@en ;
openalex:cited_by_count 129236 ;
openalex:works_count 10498 .