Regulatory T Cell Development and Function leaf node


URI

https://openalex.org/T10031

Label

Regulatory T Cell Development and Function

Description

This cluster of papers focuses on the development, function, and regulation of regulatory T cells (Tregs), particularly emphasizing the role of transcription factor Foxp3, TGF-ß induction, immune tolerance, thymic selection, memory T cells, IL-2 signaling, and their involvement in tumor immunity and immunological surveillance. The cluster also explores the implications of Tregs in autoimmunity and their potential for therapeutic interventions.

Implementation

@prefix oasubfields: <https://openalex.org/subfields/> .
@prefix openalex: <https://lambdamusic.github.io/openalex-hacks/ontology/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://openalex.org/T10031> a skos:Concept ;
    rdfs:label "Regulatory T Cell Development and Function"@en ;
    rdfs:isDefinedBy openalex: ;
    owl:sameAs <https://en.wikipedia.org/wiki/Regulatory_T_cell>,
        <https://openalex.org/T10031> ;
    skos:broader oasubfields:2403 ;
    skos:definition "This cluster of papers focuses on the development, function, and regulation of regulatory T cells (Tregs), particularly emphasizing the role of transcription factor Foxp3, TGF-ß induction, immune tolerance, thymic selection, memory T cells, IL-2 signaling, and their involvement in tumor immunity and immunological surveillance. The cluster also explores the implications of Tregs in autoimmunity and their potential for therapeutic interventions."@en ;
    skos:inScheme openalex: ;
    skos:prefLabel "Regulatory T Cell Development and Function"@en ;
    openalex:cited_by_count 3233062 ;
    openalex:works_count 72353 .