Protein Aggregation and Biopharmaceutical Stability leaf node


URI

https://openalex.org/T11124

Label

Protein Aggregation and Biopharmaceutical Stability

Description

This cluster of papers focuses on the analysis, mechanisms, and control of protein aggregation in biopharmaceuticals, particularly recombinant proteins and therapeutic antibodies. It also delves into the stability, chromatographic purification, immunogenicity, and refolding of these proteins, as well as the use of sedimentation velocity for size-distribution analysis.

Implementation

@prefix oasubfields: <https://openalex.org/subfields/> .
@prefix openalex: <https://lambdamusic.github.io/openalex-hacks/ontology/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://openalex.org/T11124> a skos:Concept ;
    rdfs:label "Protein Aggregation and Biopharmaceutical Stability"@en ;
    rdfs:isDefinedBy openalex: ;
    owl:sameAs <https://en.wikipedia.org/wiki/Protein_aggregation>,
        <https://openalex.org/T11124> ;
    skos:broader oasubfields:1312 ;
    skos:definition "This cluster of papers focuses on the analysis, mechanisms, and control of protein aggregation in biopharmaceuticals, particularly recombinant proteins and therapeutic antibodies. It also delves into the stability, chromatographic purification, immunogenicity, and refolding of these proteins, as well as the use of sedimentation velocity for size-distribution analysis."@en ;
    skos:inScheme openalex: ;
    skos:prefLabel "Protein Aggregation and Biopharmaceutical Stability"@en ;
    openalex:cited_by_count 725642 ;
    openalex:works_count 34269 .