Amyotrophic Lateral Sclerosis and Frontotemporal Dementia leaf node


URI

https://openalex.org/T10855

Label

Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

Description

This cluster of papers focuses on the molecular mechanisms, genetics, and pathology of Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD). It covers topics such as TDP-43, FUS/TLS, C9ORF72 mutations, neurodegeneration of motor neurons, RNA processing, progranulin deficiency, ubiquitin-positive inclusions, and the genetic underpinnings of these diseases.

Implementation

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@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://openalex.org/T10855> a skos:Concept ;
    rdfs:label "Amyotrophic Lateral Sclerosis and Frontotemporal Dementia"@en ;
    rdfs:isDefinedBy openalex: ;
    owl:sameAs <https://en.wikipedia.org/wiki/Amyotrophic_lateral_sclerosis>,
        <https://openalex.org/T10855> ;
    skos:broader oasubfields:2728 ;
    skos:definition "This cluster of papers focuses on the molecular mechanisms, genetics, and pathology of Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD). It covers topics such as TDP-43, FUS/TLS, C9ORF72 mutations, neurodegeneration of motor neurons, RNA processing, progranulin deficiency, ubiquitin-positive inclusions, and the genetic underpinnings of these diseases."@en ;
    skos:inScheme openalex: ;
    skos:prefLabel "Amyotrophic Lateral Sclerosis and Frontotemporal Dementia"@en ;
    openalex:cited_by_count 1218481 ;
    openalex:works_count 40005 .