Mechanisms of Drug-Induced Hepatotoxicity leaf node


URI

https://openalex.org/T11465

Label

Mechanisms of Drug-Induced Hepatotoxicity

Description

This cluster of papers focuses on the mechanisms, risk factors, biomarkers, and management of drug-induced hepatotoxicity, with a specific emphasis on acetaminophen-induced liver injury. It covers topics such as oxidative stress, mitochondrial dysfunction, HLA genotype associations, idiosyncratic reactions, and the role of liver transplantation in severe cases.

Implementation

@prefix oasubfields: <https://openalex.org/subfields/> .
@prefix openalex: <https://lambdamusic.github.io/openalex-hacks/ontology/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://openalex.org/T11465> a skos:Concept ;
    rdfs:label "Mechanisms of Drug-Induced Hepatotoxicity"@en ;
    rdfs:isDefinedBy openalex: ;
    owl:sameAs <https://en.wikipedia.org/wiki/Drug-induced_liver_injury>,
        <https://openalex.org/T11465> ;
    skos:broader oasubfields:3004 ;
    skos:definition "This cluster of papers focuses on the mechanisms, risk factors, biomarkers, and management of drug-induced hepatotoxicity, with a specific emphasis on acetaminophen-induced liver injury. It covers topics such as oxidative stress, mitochondrial dysfunction, HLA genotype associations, idiosyncratic reactions, and the role of liver transplantation in severe cases."@en ;
    skos:inScheme openalex: ;
    skos:prefLabel "Mechanisms of Drug-Induced Hepatotoxicity"@en ;
    openalex:cited_by_count 747569 ;
    openalex:works_count 61276 .