Chromatin Remodeling in Cancer and Development leaf node


URI

https://openalex.org/T12820

Label

Chromatin Remodeling in Cancer and Development

Description

This cluster of papers focuses on the role of chromatin remodeling, particularly the SWI/SNF complexes and ARID1A mutations, in cancer development and progression. It explores the impact of these mutations on epigenetic regulation, tumor suppression, genomic analysis, oncogenic transformation, and synthetic lethality. Additionally, it delves into the involvement of chromatin remodeling in mammalian development.

Implementation

@prefix oasubfields: <https://openalex.org/subfields/> .
@prefix openalex: <https://lambdamusic.github.io/openalex-hacks/ontology/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://openalex.org/T12820> a skos:Concept ;
    rdfs:label "Chromatin Remodeling in Cancer and Development"@en ;
    rdfs:isDefinedBy openalex: ;
    owl:sameAs <https://en.wikipedia.org/wiki/Chromatin_remodeling>,
        <https://openalex.org/T12820> ;
    skos:broader oasubfields:1312 ;
    skos:definition "This cluster of papers focuses on the role of chromatin remodeling, particularly the SWI/SNF complexes and ARID1A mutations, in cancer development and progression. It explores the impact of these mutations on epigenetic regulation, tumor suppression, genomic analysis, oncogenic transformation, and synthetic lethality. Additionally, it delves into the involvement of chromatin remodeling in mammalian development."@en ;
    skos:inScheme openalex: ;
    skos:prefLabel "Chromatin Remodeling in Cancer and Development"@en ;
    openalex:cited_by_count 287886 ;
    openalex:works_count 12492 .