Ubiquitin-Proteasome Proteolytic Pathway leaf node


URI

https://openalex.org/T11041

Label

Ubiquitin-Proteasome Proteolytic Pathway

Description

This cluster of papers focuses on the Ubiquitin-Proteasome Proteolytic Pathway, exploring mechanisms of protein degradation, regulation of E3 Ubiquitin Ligases, roles of Deubiquitinating Enzymes, and the impact of SUMOylation. It also delves into the development of proteasome inhibitors for cancer therapy and the involvement of this pathway in NF-?B activation.

Implementation

@prefix oasubfields: <https://openalex.org/subfields/> .
@prefix openalex: <https://lambdamusic.github.io/openalex-hacks/ontology/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://openalex.org/T11041> a skos:Concept ;
    rdfs:label "Ubiquitin-Proteasome Proteolytic Pathway"@en ;
    rdfs:isDefinedBy openalex: ;
    owl:sameAs <https://en.wikipedia.org/wiki/Ubiquitin%E2%80%93proteasome_system>,
        <https://openalex.org/T11041> ;
    skos:broader oasubfields:1312 ;
    skos:definition "This cluster of papers focuses on the Ubiquitin-Proteasome Proteolytic Pathway, exploring mechanisms of protein degradation, regulation of E3 Ubiquitin Ligases, roles of Deubiquitinating Enzymes, and the impact of SUMOylation. It also delves into the development of proteasome inhibitors for cancer therapy and the involvement of this pathway in NF-?B activation."@en ;
    skos:inScheme openalex: ;
    skos:prefLabel "Ubiquitin-Proteasome Proteolytic Pathway"@en ;
    openalex:cited_by_count 1896853 ;
    openalex:works_count 58477 .