Role of Pim Oncogenes in Tumorigenesis leaf node


URI

https://openalex.org/T13779

Label

Role of Pim Oncogenes in Tumorigenesis

Description

This cluster of papers focuses on the role of Pim oncogenes, particularly Pim-1 and Pim-2 kinases, in promoting tumorigenesis, cancer progression, and metastasis. The cluster also explores the potential of targeting Pim kinases as a therapeutic approach, with a specific emphasis on their involvement in cell survival pathways, phosphorylation of key proteins, and their association with hematological malignancies.

Implementation

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@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://openalex.org/T13779> a skos:Concept ;
    rdfs:label "Role of Pim Oncogenes in Tumorigenesis"@en ;
    rdfs:isDefinedBy openalex: ;
    owl:sameAs <https://en.wikipedia.org/wiki/PIM1>,
        <https://openalex.org/T13779> ;
    skos:broader oasubfields:2734 ;
    skos:definition "This cluster of papers focuses on the role of Pim oncogenes, particularly Pim-1 and Pim-2 kinases, in promoting tumorigenesis, cancer progression, and metastasis. The cluster also explores the potential of targeting Pim kinases as a therapeutic approach, with a specific emphasis on their involvement in cell survival pathways, phosphorylation of key proteins, and their association with hematological malignancies."@en ;
    skos:inScheme openalex: ;
    skos:prefLabel "Role of Pim Oncogenes in Tumorigenesis"@en ;
    openalex:cited_by_count 211329 ;
    openalex:works_count 19493 .