Nucleotide Metabolism and Enzyme Regulation leaf node


URI

https://openalex.org/T12827

Label

Nucleotide Metabolism and Enzyme Regulation

Description

This cluster of papers focuses on the intricate regulation and metabolic pathways of nucleotide biosynthesis, including purine and pyrimidine biosynthesis. It explores the structure, function, and inhibition of key enzymes such as CTP synthase, IMP dehydrogenase, and dihydroorotate dehydrogenase. The cluster also delves into disorders related to nucleotide metabolism, such as Lesch-Nyhan syndrome.

Implementation

@prefix oasubfields: <https://openalex.org/subfields/> .
@prefix openalex: <https://lambdamusic.github.io/openalex-hacks/ontology/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://openalex.org/T12827> a skos:Concept ;
    rdfs:label "Nucleotide Metabolism and Enzyme Regulation"@en ;
    rdfs:isDefinedBy openalex: ;
    owl:sameAs <https://en.wikipedia.org/wiki/Nucleotide_metabolism>,
        <https://openalex.org/T12827> ;
    skos:broader oasubfields:1312 ;
    skos:definition "This cluster of papers focuses on the intricate regulation and metabolic pathways of nucleotide biosynthesis, including purine and pyrimidine biosynthesis. It explores the structure, function, and inhibition of key enzymes such as CTP synthase, IMP dehydrogenase, and dihydroorotate dehydrogenase. The cluster also delves into disorders related to nucleotide metabolism, such as Lesch-Nyhan syndrome."@en ;
    skos:inScheme openalex: ;
    skos:prefLabel "Nucleotide Metabolism and Enzyme Regulation"@en ;
    openalex:cited_by_count 1017589 ;
    openalex:works_count 53009 .